Kluger N
Departments of Dermatology, Allergology and Venereology, Institute of Clinical Medicine, University of Helsinki, Skin and Allergies Hospital,Helsinki University Central Hospital, Finland.
Sarcoidosis Vasc Diffuse Lung Dis. 2013 Aug 1;30(2):86-102.
Sarcoidosis is an autoimmune disease of unknown etiology characterized by the presence of non-caseating epithelioid cell granulomas in multiple organs. Cutaneous sarcoidosis occurs in approximately 25% of the cases. Sarcoid reactions on old scars, traumatized skin sites and around embedded foreign material have long been observed. For the past 70 years, sarcoidal granulomas on tattoos and permanent make-up have also been documented. Granulomatous and sarcoidal tattoo reactions may be the first and sometimes only cutaneous manifestation of systemic sarcoidosis. This review summarizes the currently available data on this topic and discusses the issues related to the diagnosis, management and physiopathogeny of sarcoidal reactions on tattoos.
结节病是一种病因不明的自身免疫性疾病，其特征是多个器官存在非干酪样上皮样细胞肉芽肿。皮肤结节病约见于25%的病例。长期以来，人们一直观察到旧瘢痕、创伤皮肤部位以及植入异物周围出现结节病反应。在过去70年中，纹身和纹眉部位出现结节样肉芽肿也有文献记载。肉芽肿性和结节样纹身反应可能是系统性结节病的首发表现，有时也是唯一的皮肤表现。本文综述了该主题的现有数据，并讨论了与纹身结节样反应的诊断、管理和发病机制相关的问题。
