脂质和尿毒症毒素在 CKD 心血管疾病中的作用。
The role of lipids and uremic toxins in cardiovascular disease in CKD.
机构信息
Division of Nephrology, Ambroise Paré Hospital, Paris Ile de France Ouest University (UVSQ), 09 Avenue Charles de Gaulle, Boulogne Billancourt, 92100, Paris, France,
出版信息
Clin Exp Nephrol. 2014 Apr;18(2):255-6. doi: 10.1007/s10157-013-0864-y. Epub 2013 Sep 27.
PMID:24072415
Abstract
Lipid abnormalities and uremic toxins are features of chronic kidney disease (CKD) and may influence cardiovascular outcomes in CKD patients. Recent data suggest that uremic toxins may modulate lipoprotein levels and composition (e.g., oxidation or carbamylation) and enhance the cardiovascular toxicity of lipoproteins in CKD patients.
摘要
脂类异常和尿毒症毒素是慢性肾脏病（CKD）的特征，可能影响 CKD 患者的心血管结局。最近的数据表明，尿毒症毒素可能调节脂蛋白水平和组成（例如，氧化或氨甲酰化），并增强 CKD 患者脂蛋白的心血管毒性。
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