Namburi Rajendra Prasad, Karthik Takkolu Sriram, Ponnala Amaresh Reddy
Department of Endocrinology and Metabolism, Narayana Medical College and Superspeciality Hospital, Nellore, 524003, India.
Indian J Pediatr. 2014 Sep;81(9):937-9. doi: 10.1007/s12098-013-1221-6. Epub 2013 Sep 27.
Pituitary hyperplasia with hyperprolactinemia has been described as a rare presentation of primary hypothyroidism. A 12-y-old child presented with intermittent headache, easy fatigability, coarseness of facial features, and hoarseness of voice for 6 mo duration. Brain imaging findings showed pituitary hyperplasia; hormonal assessment revealed primary hypothyroidism and hyperprolactinemia. Pituitary hyperplasia regressed with thyroid hormone replacement therapy. This report describes an unusual case of pituitary hyperplasia with hyperprolactinemia secondary to primary hypothyroidism.
垂体增生伴高催乳素血症被描述为原发性甲状腺功能减退症的一种罕见表现。一名12岁儿童出现间歇性头痛、易疲劳、面部特征粗糙和声音嘶哑，持续6个月。脑部影像学检查发现垂体增生；激素评估显示原发性甲状腺功能减退症和高催乳素血症。垂体增生经甲状腺激素替代治疗后消退。本报告描述了一例由原发性甲状腺功能减退症继发的垂体增生伴高催乳素血症的罕见病例。
