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原发性甲状腺功能减退症伴颅内高压和垂体增生。

Primary hypothyroidism with intracranial hypertension and pituitary hyperplasia.

作者信息

Adams C, Dean H J, Israels S J, Patton A, Fewer D H

机构信息

Department of Neurology, Children's Hospital, Winnipeg, Manitoba, Canada.

出版信息

Pediatr Neurol. 1994 Mar;10(2):166-8. doi: 10.1016/0887-8994(94)90053-1.

DOI:10.1016/0887-8994(94)90053-1
PMID:8024669
Abstract

A 12-year-old girl presented with primary hypothyroidism, secondary pituitary hyperplasia, and intracranial hypertension. Cranial computed tomography revealed a sellar mass with suprasellar extension. She responded to medical treatment. Intracranial hypertension may be associated with primary hypothyroidism prior to thyroxine treatment. Because significant pituitary hyperplasia can be associated with primary hypothyroidism, it is vital to have endocrine investigation prior to consideration of surgical removal of an apparent pituitary tumor.

摘要

一名12岁女孩出现原发性甲状腺功能减退、继发性垂体增生和颅内高压。头颅计算机断层扫描显示鞍区有肿块并向上延伸至鞍上。她对药物治疗有反应。在甲状腺素治疗前,颅内高压可能与原发性甲状腺功能减退有关。由于明显的垂体增生可能与原发性甲状腺功能减退有关,因此在考虑手术切除明显的垂体肿瘤之前进行内分泌检查至关重要。

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Pituitary hyperplasia in childhood primary hypothyroidism: a review.儿童原发性甲状腺功能减退症中的垂体增生:综述。
Childs Nerv Syst. 2021 Mar;37(3):749-762. doi: 10.1007/s00381-020-05014-6. Epub 2021 Jan 6.
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Primary hypothyroidism in a child simulating a prolactin-secreting adenoma.儿童原发性甲状腺功能减退症模拟催乳素分泌性腺瘤。
Childs Nerv Syst. 2008 Dec;24(12):1505-8. doi: 10.1007/s00381-008-0689-2. Epub 2008 Aug 9.