三株非洲2型幽门螺杆菌的基因组序列
Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori.
作者信息
Duncan Stacy S, Bertoli M Teresita, Kersulyte Dangeruta, Valk Pieter L, Tamma Sravya, Segal Issy, McClain Mark S, Cover Timothy L, Berg Douglas E
机构信息
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
出版信息
Genome Announc. 2013 Sep 26;1(5):e00729-13. doi: 10.1128/genomeA.00729-13.
Abstract
We present the genome sequences of three hpAfrica2 strains of Helicobacter pylori, which are postulated to have evolved in isolation for many millennia in people of San ethnicity. Although previously considered to be ancestral to Helicobacter acinonychis, the hpAfrica2 strains differ markedly from H. acinonychis in their gene arrangement. These data provide new insights into Helicobacter evolution.
摘要
我们展示了三株幽门螺杆菌hpAfrica2菌株的基因组序列，据推测这些菌株在桑族人群中已经独立进化了数千年。尽管之前认为hpAfrica2菌株是非洲狮幽门螺杆菌的祖先，但hpAfrica2菌株在基因排列上与非洲狮幽门螺杆菌明显不同。这些数据为幽门螺杆菌的进化提供了新的见解。
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