通过光氧化还原催化断裂叔烷基 N-邻苯二甲酰亚胺基草酸盐，从叔醇直接构建季碳原子。
Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates.
机构信息
Department of Chemistry, University of California , Irvine, California 92697-2025, United States.
出版信息
J Am Chem Soc. 2013 Oct 16;135(41):15342-5. doi: 10.1021/ja408971t. Epub 2013 Oct 2.
Abstract
A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.
摘要
本文报道了一种方便的方法，通过叔烷基 N-邻苯二甲酰亚胺基草酰酯中间体与缺电子烯烃的可见光光氧化还原偶联，直接从叔醇构建季碳原子。
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