Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland; Department of Health Education, University of Szczecin, Piastow 40B, 71-065 Szczecin, Poland.
Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
J Trace Elem Med Biol. 2014 Jan;28(1):39-44. doi: 10.1016/j.jtemb.2013.07.004. Epub 2013 Jul 24.
The aim of this study was to determine the concentrations of manganese (Mn), iron (Fe) and strontium (Sr) in the cartilage with adjacent compact bone and spongy bone collected from patients after total hip replacement surgery. In addition, we examined relations between the concentrations of the metals in the bone and selected environmental factors. The concentration of Fe was the highest while Mn concentration was the lowest. The concentrations of Fe in the spongy bone in patients from larger cities were higher than in those living in smaller towns and villages. Significant correlations were found between Fe and Mn concentrations in the cartilage with adjacent compact bone and in the spongy bone, and between Mn and Sr in the spongy bone. In general, Mn, Fe and Sr concentrations in the bones of patients from NW Poland were lower than in other Polish regions and Europe, especially in industrialized countries. In conclusion, it seems that in addition to routine monitoring of the abiotic environment, it is essential to monitor concentrations of heavy metals having a long-term impact in humans.
本研究旨在测定全髋关节置换术后患者关节软骨及其相邻密质骨和松质骨中锰（Mn）、铁（Fe）和锶（Sr）的浓度。此外，我们还研究了骨骼中金属浓度与选定环境因素之间的关系。Fe 的浓度最高，Mn 的浓度最低。来自大城市的患者的松质骨中的 Fe 浓度高于来自小城镇和村庄的患者。在软骨及其相邻密质骨和松质骨中，Fe 和 Mn 浓度之间以及在松质骨中 Mn 和 Sr 浓度之间存在显著相关性。一般来说，来自波兰西北部的患者的骨骼中的 Mn、Fe 和 Sr 浓度低于波兰其他地区和欧洲，尤其是工业化国家。总之，除了对非生物环境进行常规监测外，监测对人类具有长期影响的重金属浓度也很重要。
