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Iron, Zinc, Copper, Cadmium, Mercury, and Bone Tissue.铁、锌、铜、镉、汞与骨组织。
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Biological and health implications of toxic heavy metal and essential trace element interactions.有毒重金属与必需微量元素相互作用的生物学及健康影响
Prog Food Nutr Sci. 1987;11(1):55-113.
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[Bioavailability from foods of trace elements: iron, zinc, copper, selenium, chromium, lead, cadmium, mercury].[食物中微量元素的生物利用率:铁、锌、铜、硒、铬、铅、镉、汞]
Ann Ist Super Sanita. 1984;20(2-3):149-69.
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Comparison of metal concentrations in bones of long-living mammals.长寿哺乳动物骨骼中金属浓度的比较。
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本文引用的文献

1
Effects of inorganic mercury exposure in the alveolar bone of rats: an approach of qualitative and morphological aspects.无机汞暴露对大鼠肺泡骨的影响:定性和形态学方法。
PeerJ. 2022 Jan 26;10:e12573. doi: 10.7717/peerj.12573. eCollection 2022.
2
Copper as Dietary Supplement for Bone Metabolism: A Review.铜作为膳食补充剂对骨骼代谢的影响:综述。
Nutrients. 2021 Jun 29;13(7):2246. doi: 10.3390/nu13072246.
3
Natural incorporation of mercury in bone.汞在骨组织中的自然摄入。
J Trace Elem Med Biol. 2021 Sep;67:126797. doi: 10.1016/j.jtemb.2021.126797. Epub 2021 May 28.
4
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue.钙、镁、磷、氟和铅对骨组织的影响。
Biomolecules. 2021 Mar 28;11(4):506. doi: 10.3390/biom11040506.
5
Influence of Cu on Osteoclast Formation and Activity In Vitro.Cu 对体外破骨细胞形成和活性的影响。
Int J Mol Sci. 2021 Feb 28;22(5):2451. doi: 10.3390/ijms22052451.
6
The role of TGF-β1/Smad3 signaling pathway and oxidative stress in the inhibition of osteoblast mineralization by copper chloride.氯化铜抑制成骨细胞矿化过程中 TGF-β1/Smad3 信号通路和氧化应激的作用
Environ Toxicol Pharmacol. 2021 May;84:103613. doi: 10.1016/j.etap.2021.103613. Epub 2021 Feb 8.
7
Adverse Impact of Heavy Metals on Bone Cells and Bone Metabolism Dependently and Independently through Anemia.重金属通过贫血对骨细胞和骨代谢产生的依赖和非依赖的不良影响。
Adv Sci (Weinh). 2020 Aug 4;7(19):2000383. doi: 10.1002/advs.202000383. eCollection 2020 Oct.
8
The Role of Fe, Zn, and Cu in Pregnancy.铁、锌和铜在妊娠中的作用。
Biomolecules. 2020 Aug 12;10(8):1176. doi: 10.3390/biom10081176.
9
The Effects of Cadmium Toxicity.镉毒性的影响。
Int J Environ Res Public Health. 2020 May 26;17(11):3782. doi: 10.3390/ijerph17113782.
10
Zinc as a Therapeutic Agent in Bone Regeneration.锌作为骨再生的治疗剂。
Materials (Basel). 2020 May 12;13(10):2211. doi: 10.3390/ma13102211.

铁、锌、铜、镉、汞与骨组织。

Iron, Zinc, Copper, Cadmium, Mercury, and Bone Tissue.

机构信息

Chair and Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 54, 70-210 Szczecin, Poland.

Department of Biology and Medical Parasitology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.

出版信息

Int J Environ Res Public Health. 2023 Jan 26;20(3):2197. doi: 10.3390/ijerph20032197.

DOI:10.3390/ijerph20032197
PMID:36767564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9915283/
Abstract

The paper presents the current understanding on the effects of five metals on bone tissue, namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute significantly to human and animal metabolism when present in sufficient amounts, but their excess or shortage increases the risk of developing bone disorders. In contrast, cadmium and mercury serve no physiological purpose and their long-term accumulation damages the osteoarticular system. We discuss the methods of action and interactions between the discussed elements as well as the concentrations of each element in distinct bone structures.

摘要

本文介绍了目前人们对五种金属(铁、锌、铜、镉和汞)对骨骼组织影响的认识。在适量存在的情况下,铁、锌和铜对人体和动物的新陈代谢有重要贡献,但过量或缺乏会增加骨骼疾病的风险。相比之下,镉和汞没有生理作用,它们的长期积累会损害骨-关节系统。我们讨论了所讨论元素的作用方式和相互作用,以及每个元素在不同骨骼结构中的浓度。