Department of Biology and Medical Parasitology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
J Trace Elem Med Biol. 2012 Jan;26(1):20-5. doi: 10.1016/j.jtemb.2011.11.006. Epub 2012 Feb 24.
The aim of this research was to determine the concentrations of two essential elements (copper (Cu) and zinc (Zn)) and three toxic elements (lead (Pb), cadmium (Cd) and mercury (Hg)) in the hip joint bones of patients from the Chair and Clinic of Orthopaedics and Traumatology at the Pomeranian Medical University in Szczecin. We examined 111 samples of hip joint bones obtained from patients from north-western Poland who had undergone arthroplasty of the femoral head. In cartilage with the adjacent compact bone, and in spongy bone from the examined patients, the concentrations (medians) determined were placed in the following descending sequence Zn>Pb>Cu>Cd>Hg. The concentrations ranged from 86 mg Zn/kg to 0.0020 mg Hg/kg dw. It was found that the concentration of lead in the cartilage with adjacent compact bone was higher in men than in women. In conclusion, it seems that in addition to routine monitoring of the abiotic environment, it is essential to monitor concentrations of heavy metals having a long-term impact in humans.
本研究旨在测定波兰西北部接受股骨头置换术的患者髋关节骨中两种必需元素（铜（Cu）和锌（Zn））和三种有毒元素（铅（Pb）、镉（Cd）和汞（Hg））的浓度。我们检查了来自什切青波美拉尼亚医科大学矫形外科和创伤学主席和诊所的 111 名患者的髋关节骨样本。在软骨与相邻的密质骨，以及来自受检患者的海绵骨中，确定的浓度（中位数）按以下降序排列 Zn>Pb>Cu>Cd>Hg。浓度范围从 86 毫克 Zn/kg 到 0.0020 毫克 Hg/kg dw。结果发现，男性软骨与相邻密质骨中的铅浓度高于女性。总之，除了对非生物环境进行常规监测外，对具有长期人类影响的重金属浓度进行监测也很重要。
