Nguyen Geoffrey C, Chong Christopher A, Chong Rachel Y
Mount Sinai Hospital Centre for Inflammatory Bowel Disease, University of Toronto, Toronto, Ontario, Canada; Institute for Health Policy Management and Evaluation, University of Toronto, Canada; Division of Gastroenterology and Hepatology, Johns Hopkins School of Medicine, USA.
Department of Medicine, Lakeridge Health, Oshawa, Ontario, Canada.
J Crohns Colitis. 2014 Apr;8(4):288-95. doi: 10.1016/j.crohns.2013.09.001. Epub 2013 Sep 24.
The epidemiology of inflammatory bowel disease (IBD) is poorly characterized in minorities in the U.S. We sought to enumerate the burden of IBD among racial and ethnic groups using national-level data.
Data from the National Health Interview Survey was used to calculate prevalence and incidence of IBD among adults (≥ 18 years) in 1999. The Nationwide Inpatient Sample was queried to ascertain rates of IBD-related hospitalizations and the Underlying Cause of Death Database was accessed to quantify IBD-related mortality.
An estimated 1,810,773 adult Americans were affected by IBD yielding a prevalence of 908/100,000, which was higher in Non-Hispanic Whites (1099/100,000) compared with Non-Hispanic Blacks (324/100,000), Hispanics (383/100,000), and non-Hispanic Other (314/100,000). Relative to Non-Hispanic Whites, the odds ratios for having a diagnosis of IBD associated with being Non-Hispanic Black, Hispanic, and Other Non-Hispanic race after adjusting for age, sex, and geographic region were 0.33 (95% CI: 0.19 - 0.57), 0.45 (95% CI: 0.26 - 0.77), and 0.34 (95% CI: 0.12 - 0.93), respectively. IBD incidence was similarly lower in Non-Hispanic Blacks (24.9/100,000) and Hispanics (9.9/100,000) compared to Non-Hispanic Whites (70.2/100,000). The ratio of IBD hospitalizations to prevalence was disproportionately higher among Non-Hispanic Blacks (7.3%) compared with Non-Hispanic Whites (3.0%) and Hispanics (2.7%). Similarly, the ratio of IBD-related mortality was greater in Non-Hispanic Blacks (0.061%) compared to Non-Hispanic Whites (0.036%) and Hispanics (0.026%).
IBD disease burden is lower in ethnic minorities compared to Non-Hispanic Whites. However, IBD-related hospitalizations and deaths seem disproportionately high in Non-Hispanic Blacks.
美国少数族裔炎症性肠病（IBD）的流行病学特征尚不明确。我们试图利用国家级数据来统计不同种族和族裔群体中IBD的负担情况。
使用来自美国国家健康访谈调查的数据来计算1999年成年人（≥18岁）中IBD的患病率和发病率。查询全国住院患者样本以确定IBD相关住院率，并访问死亡原因数据库以量化IBD相关死亡率。
估计有1,810,773名成年美国人受IBD影响，患病率为908/10万，非西班牙裔白人（1099/10万）的患病率高于非西班牙裔黑人（324/10万）、西班牙裔（383/10万）和非西班牙裔其他种族（314/10万）。在调整年龄、性别和地理区域后，相对于非西班牙裔白人，非西班牙裔黑人、西班牙裔和其他非西班牙裔种族被诊断为IBD的比值比分别为0.33（95%可信区间：0.19 - 0.57）、0.45（95%可信区间：0.26 - 0.77）和0.34（95%可信区间：0.12 - 0.93）。与非西班牙裔白人（70.2/10万）相比，非西班牙裔黑人（24.9/10万）和西班牙裔（9.9/10万）的IBD发病率同样较低。非西班牙裔黑人中IBD住院率与患病率的比值（7.3%）相对于非西班牙裔白人（3.0%）和西班牙裔（2.7%）而言过高。同样，非西班牙裔黑人中IBD相关死亡率（0.061%）高于非西班牙裔白人（0.036%）和西班牙裔（0.026%）。
与非西班牙裔白人相比，少数族裔的IBD疾病负担较低。然而，非西班牙裔黑人中IBD相关的住院率和死亡率似乎过高。
