Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX.
Urology. 2013 Oct;82(4):943-6. doi: 10.1016/j.urology.2013.06.044.
To evaluate the relative risk of prolonged urethral catheterization (PC), >48 hours, on artificial urinary sphincter (AUS) cuff erosion in a tertiary referral population.
All men who had undergone AUS implantation or revision by multiple surgeons at our institution from 2000 to 2010 with ≥6 months of follow-up were reviewed for urethral erosion, catheterization after AUS placement, and comorbid conditions.
Of the 258 AUS patients reviewed, 200 met the inclusion criteria, with an average follow-up of 24 months. AUS cuff erosions were noted in 24 men (12%) and were diagnosed at a mean of 16.9 months (range 0.8-87.1). PC was identified in 44 of the 200 men (22%)-of these men, erosions occurred in 17 (39%, P <.001). The indication for PC was most often major nongenitourinary surgery (36%) or urinary retention (32%). Univariate analysis identified an increased risk of erosion associated with hypertension, diabetes, coronary artery disease, PC, previous radiotherapy, and secondary AUS placement (P <.05). On multivariate analysis, only PC, radiotherapy, and revision surgery were significant (P <.05), but cuff size and concomitant inflatable penile prosthesis were not associated with AUS cuff erosion.
PC is an independent risk factor for AUS cuff erosion.
评估在三级转诊人群中,导尿管留置时间(PC)>48 小时与人工尿道括约肌(AUS)袖套侵蚀的相对风险。
对 2000 年至 2010 年期间在我院由多位外科医生进行 AUS 植入或翻修手术且随访时间≥6 个月的所有患者进行尿道侵蚀、AUS 放置后导尿和并存疾病的回顾性分析。
在 258 例 AUS 患者中,有 200 例符合纳入标准,平均随访时间为 24 个月。24 例(12%)男性出现 AUS 袖套侵蚀,平均诊断时间为 16.9 个月(范围 0.8-87.1)。在 200 例男性中,有 44 例(22%)发生 PC-这些男性中,17 例(39%,P<.001)发生侵蚀。PC 的指征主要是重大非泌尿生殖系统手术(36%)或尿潴留(32%)。单因素分析发现,与侵蚀相关的危险因素包括高血压、糖尿病、冠状动脉疾病、PC、既往放疗和继发性 AUS 放置(P<.05)。多因素分析发现,只有 PC、放疗和翻修手术有统计学意义(P<.05),但袖套大小和同时使用可膨胀阴茎假体与 AUS 袖套侵蚀无关。
PC 是 AUS 袖套侵蚀的独立危险因素。