Department of Oncology, University Hospital Zurich, Zurich, Switzerland.
Lung Cancer. 2013 Dec;82(3):506-8. doi: 10.1016/j.lungcan.2013.08.030. Epub 2013 Sep 8.
Here we report the case of a patient with metastatic adenocarcinoma of the lung harboring an ALK gene translocation. In this patient a response of the primary tumor and metastases has been detected upon treatment with denosumab. A possible link between ALK and RANK is postulated.
在这里,我们报告了一例患有携带 ALK 基因易位的肺转移性腺癌的患者。在该患者中,用地舒单抗治疗后检测到原发肿瘤和转移灶的反应。推测 ALK 和 RANK 之间存在可能的联系。