Fenske N A, Lober C W
Department of Internal Medicine, University of South Florida College of Medicine, Tampa.
Geriatrics. 1990 Mar;45(3):27-35.
Skin changes caused by the natural aging process (intrinsic aging), as opposed to environmental assault (extrinsic aging), are now recognized and delineated. These alterations play a role in the etiopathogenesis of many of the skin problems that develop in elderly patients. Structural and functional changes that occur in normal aging skin are discussed with respect to their relationship to common skin disorders in the elderly.
与环境侵害（外源性老化）相对，由自然衰老过程（内源性老化）引起的皮肤变化现已得到认识和描述。这些改变在老年患者出现的许多皮肤问题的病因发病机制中起作用。本文讨论了正常老化皮肤中发生的结构和功能变化及其与老年人常见皮肤疾病的关系。
