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IκBα beyond the NF-kB dogma.

作者信息

Mulero Maria Carmen, Bigas Anna, Espinosa Lluís

机构信息

Program in Cancer Research, IMIM-Hospital del Mar, Barcelona Biomedical Research Park (PRBB), Barcelona, Spain.

出版信息

Oncotarget. 2013 Oct;4(10):1550-1. doi: 10.18632/oncotarget.1325.

DOI:10.18632/oncotarget.1325
PMID:24077698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3858542/
Abstract
摘要

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Cancer Cell. 2013 Aug 12;24(2):151-66. doi: 10.1016/j.ccr.2013.06.003. Epub 2013 Jul 11.
2
IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response.IkappaBbeta 在炎症反应过程中起到抑制和激活基因表达的作用。
Nature. 2010 Aug 26;466(7310):1115-9. doi: 10.1038/nature09283.
3
IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing.
组蛋白去甲基化酶 KDM5B 通过抑制 Nfkbia 转录来许可巨噬细胞介导的炎症反应。
Cell Death Differ. 2023 May;30(5):1279-1292. doi: 10.1038/s41418-023-01136-x. Epub 2023 Mar 13.
4
Angiotensin (1-7) Attenuates Sepsis-Induced Acute Kidney Injury by Regulating the NF-κB Pathway.血管紧张素(1-7)通过调节核因子κB通路减轻脓毒症诱导的急性肾损伤。
Front Pharmacol. 2021 Mar 4;12:601909. doi: 10.3389/fphar.2021.601909. eCollection 2021.
5
Post-translational Modifications of IκBα: The State of the Art.IκBα的翻译后修饰:最新进展
Front Cell Dev Biol. 2020 Nov 5;8:574706. doi: 10.3389/fcell.2020.574706. eCollection 2020.
6
Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development.抑制κB 的祖先功能调控秀丽隐杆线虫的发育。
Sci Rep. 2020 Sep 30;10(1):16153. doi: 10.1038/s41598-020-73146-5.
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Interaction of an IκBα Peptide with 14-3-3.一种IκBα肽与14-3-3的相互作用
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Cell. 2003 Nov 26;115(5):565-76. doi: 10.1016/s0092-8674(03)00895-x.
7
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8
Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm.IκBα的核定位促进NF-κB从细胞核到细胞质的主动转运。
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