Dahlin L B, Lundborg G
Department of Hand Surgery, University of Lund, General Hospital, Malmö, Sweden.
J Hand Surg Br. 1990 Feb;15(1):5-10. doi: 10.1016/0266-7681_90_90040-b.
In all types of peripheral nerve injury, it is important to realize that the lesion affects one extended cell, the neurone, which extends from the central nervous system down to the target tissue in the extremity. Compression of a peripheral nerve can disturb the intraneural transport (axonal transport) of a large variety of substances. This may be followed by morphological and biochemical changes in the nerve cell body. These central changes may effect the axon as a whole and confer on the nerve an increased susceptibility to trauma. Studies concerning the reaction of neurones to compression, relevant when discussing the double crush syndrome, are reviewed.
在所有类型的周围神经损伤中，必须认识到损伤影响的是一个延伸的细胞，即神经元，它从中枢神经系统一直延伸到肢体的靶组织。周围神经受压会干扰多种物质的神经内运输（轴突运输）。随后，神经细胞体可能会发生形态和生化变化。这些中枢性变化可能会影响整个轴突，并使神经对外伤的易感性增加。本文综述了有关神经元对压迫反应的研究，这些研究在讨论双卡综合征时具有相关性。
