栀子胶中的环阿尔廷烷

Cycloartanes from the gum resin of Gardenia gummifera L.f.

机构信息

University College of Pharmaceutical Sciences, Kakatiya University, Warangal - 506009, Andhra Pradesh, India.

出版信息

Chem Biodivers. 2013 Sep;10(9):1613-22. doi: 10.1002/cbdv.201200383.

DOI:10.1002/cbdv.201200383

Abstract

The gum resin exuding from the leaf buds of Gardenia gummifera was investigated. Eight new cycloartane triterpenes, 1-6, 8, and 10, together with two known triterpenes, 25-hydroxycycloart-23-en-3-one (7) and cycloartenone (9), were isolated and identified by extensive NMR spectroscopy. For cycloartenone (9), full NMR assignments are given as these data were not available in the literature. Eight compounds possess a C(3)=O group, two are 3,4-secocycloartanes bearing a free C(3)OOH group; in one of the cycloartanes, gummiferartane-9 (10), ring A occurs as a seven-membered lactone.

摘要

从黄栀子的叶芽中提取的树胶树脂进行了研究。分离并鉴定了八种新的环阿尔泰烷三萜，1-6、8 和 10，以及两种已知的三萜，25-羟基环阿尔泰-23-烯-3-酮（7）和环阿尔泰酮（9）。对于环阿尔泰酮（9），给出了完整的 NMR 分配，因为这些数据在文献中不可用。有八种化合物具有 C(3)=O 基团，两种是具有游离 C(3)OOH 基团的 3,4-双环阿尔泰烷；在其中一种环阿尔泰烷，黄栀子烷-9（10）中，A 环为七元内酯。