栀子苷E-H，来自钝叶栀子顶芽的环阿尔廷烷三萜类化合物。

Gardenoins E-H, cycloartane triterpenes from the apical buds of Gardenia obtusifolia.

作者信息

Nuanyai Thanesuan, Sappapan Ruengrit, Vilaivan Tirayut, Pudhom Khanitha

机构信息

Research Centre of Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

出版信息

Chem Pharm Bull (Tokyo). 2011;59(3):385-7. doi: 10.1248/cpb.59.385.

DOI:10.1248/cpb.59.385

PMID:21372423

Abstract

Four new cycloartane triterpenes, named gardenoins E-H (1-4), were isolated from the apical buds of Gardenia obtusifolia, together with five known cycloartanes. Only compound 1 displayed cytotoxicity against colon, hepatic and lung cancer cell lines.

摘要

从钝叶栀子的顶芽中分离出四种新的环阿尔廷烷三萜，命名为栀子苷E - H（1 - 4），以及五种已知的环阿尔廷烷。只有化合物1对结肠、肝癌和肺癌细胞系具有细胞毒性。