INVEX——一个基于网络的用于表达数据综合可视化的工具。
INVEX--a web-based tool for integrative visualization of expression data.
机构信息
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z3, Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, Canada V6T 1Z4 and Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
出版信息
Bioinformatics. 2013 Dec 15;29(24):3232-4. doi: 10.1093/bioinformatics/btt562. Epub 2013 Sep 26.
SUMMARY
Gene expression or metabolomics data generated from clinical settings are often associated with multiple metadata (i.e. diagnosis, genotype, gender, etc.). It is of great interest to analyze and to visualize the data in these contexts. Here, we introduce INVEX-a novel web-based tool that integrates the server-side capabilities for data analysis with the browse-based technology for data visualization. INVEX has two key features: (i) flexible differential expression analysis for a wide variety of experimental designs; and (ii) interactive visualization within the context of metadata and biological annotations. INVEX has built-in support for gene/metabolite annotation and a fully functional heatmap builder.
AVAILABILITY AND IMPLEMENTATION
Freely available at http://www.invex.ca.
摘要
从临床环境中生成的基因表达或代谢组学数据通常与多个元数据（即诊断、基因型、性别等）相关联。在这些情况下分析和可视化数据是非常有意义的。在这里，我们介绍了 INVEX，这是一种新型的基于网络的工具，它将服务器端的数据分析功能与基于浏览的数据可视化技术集成在一起。INVEX 具有两个关键特性：（i）灵活的差异表达分析，适用于各种实验设计；（ii）在元数据和生物学注释的背景下进行交互式可视化。INVEX 内置了对基因/代谢物注释的支持和一个功能齐全的热图生成器。
可用性和实现
可在 http://www.invex.ca 上免费获得。
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