Gastroenterology and Hepatology Center, Fundeni Clinical Institute, Bucharest, Romania; Email:
J Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.
The aim of the present study was to characterize the dynamics of the Romanian waiting list (WL) for liver transplantation (LT) over two periods: 2004-2007 vs. 2008-2011.
1,085 patients listed for LT during the time period 2004-2011 were included in our analysis.
Death on the WL was significantly higher before 2008 (37% vs. 26.4%, p=0.0001) and risk of dying while on WL was 60% higher. Waiting time on the WL was 75% longer and time until LT was 102% longer before 2008 compared to the second time period (p=0.0001). After 2008, 62.3% of patients were listed for LT with Child Pugh class C compared to 22.1% before 2008 (p<0.0001).
A significant reduction of mortality has been registered on the Romanian WL for LT after 2008, despite the increased severity of liver disease in patients listed for LT.
本研究旨在描述罗马尼亚肝移植(LT)等待名单(WL)在两个时期的动态:2004-2007 年与 2008-2011 年。
我们分析了 2004-2011 年期间列入 LT 名单的 1085 名患者。
2008 年之前 WL 上的死亡率显著更高(37%比 26.4%,p=0.0001),而 WL 上的死亡风险高 60%。与第二个时期相比,2008 年之前 WL 上的等待时间长 75%,LT 时间长 102%(p=0.0001)。2008 年后,62.3%的患者被列入 LT 名单,而在 2008 年之前,Child-Pugh 分级为 C 的患者比例为 22.1%(p<0.0001)。
尽管 LT 患者的肝病严重程度增加,但 2008 年后罗马尼亚 LT 等待名单上的死亡率显著下降。