Taremi Mahnaz, Amoroso Anthony, Nace Heather L, Gilliam Bruce L
Institute of Human Virology and Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, USA.
BMC Infect Dis. 2013 Sep 30;13:452. doi: 10.1186/1471-2334-13-452.
An association between influenza A viruses and myocarditis was noted during the 1918 influenza pandemic. Since then, the link between the influenza B virus and fulminant myocarditis or cardiogenic shock has been rarely reported.
In February 2013, a 50 year-old-woman without known heart disease presented in profound cardiogenic shock with a left ventricular ejection fraction of 10%. Her presentation was preceded by six days of fever, chills, myalgia and fatigue. She had a junctional tachycardia, a troponin I of 12.6 ng/ml and her coronary angiography demonstrated normal coronary arteries. Percutaneous extracorporeal membrane oxygenation was required. An endotracheal aspirate at admission was positive for influenza B. All other respiratory, blood and urine cultures were negative. On day 7, a repeat echocardiography demonstrated significant recovery of left ventricular function with an ejection fraction of 50%. She was later discharged home in good condition.
Influenza B infection can be complicated by fulminant cardiomyopathy leading to cardiogenic shock in adults without preexisting cardiac disease.
1918年流感大流行期间发现甲型流感病毒与心肌炎之间存在关联。从那时起，乙型流感病毒与暴发性心肌炎或心源性休克之间的联系鲜有报道。
2013年2月，一名无已知心脏病史的50岁女性出现严重的心源性休克，左心室射血分数为10%。在出现症状之前，她有六天的发热、寒战、肌痛和疲劳。她出现交界性心动过速，肌钙蛋白I为12.6 ng/ml，冠状动脉造影显示冠状动脉正常。需要进行经皮体外膜肺氧合。入院时气管内吸出物乙型流感检测呈阳性。所有其他呼吸道、血液和尿液培养均为阴性。第7天，重复超声心动图显示左心室功能显著恢复，射血分数为50%。她后来康复出院。
乙型流感感染可并发暴发性心肌病，导致无心脏病史的成年人发生心源性休克。
