Dermatology Clinic, Hospital do Servidor Público Municipal de São Paulo, Sao Paulo, Brazil.
Clin Dermatol. 2013 Sep-Oct;31(5):594-601. doi: 10.1016/j.clindermatol.2013.06.007.
Melanonychia is black or brown pigmentation that appears in the fingernails and toenails. The pigment can come from exogenous sources, such as bacteria or fungal infection, tar, or blood. Endogenous causes include aberrant melanin production in the nail bed, resulting in a longitudinal presentation. Melanonychia can indicate the presence of cancerous growths, as well as infection. Diagnostic measures, including dermatoscopy, biopsy, and histopathology, can determine the cause and direct the course of treatment. Malignant lesions should be excised, and underlying infections should be addressed with antibiotics or antifungals. Benign lesions and hyperpigmentation may benefit from a wait-and-see approach.
甲下黑色素沉着是指出现在手指甲和脚趾甲中的黑色或棕色色素沉着。这种色素可能来自于外源性来源,如细菌或真菌感染、焦油或血液。内源性原因包括甲床中异常的黑色素生成,导致纵向出现。甲下黑色素沉着可能表明存在癌性生长以及感染。诊断措施包括皮肤镜检查、活检和组织病理学检查,可以确定病因并指导治疗过程。恶性病变应切除,感染应使用抗生素或抗真菌药物治疗。良性病变和色素沉着过度可能受益于观察等待方法。