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印度口腔保健提供者的抗生素处方模式:一项横断面调查。

Antibiotic prescription pattern among Indian oral healthcare providers: a cross-sectional survey.

机构信息

Department of Conservative Dentistry and Endodontics, Modern Dental College and Research Centre, Indore, India.

出版信息

J Antimicrob Chemother. 2014 Feb;69(2):526-8. doi: 10.1093/jac/dkt351. Epub 2013 Sep 29.

Abstract

OBJECTIVES

Inappropriate prescribing of antibiotics by healthcare professionals is a worldwide concern. The purpose of this study was to determine the pattern of antibiotic prescription among oral healthcare providers in India.

METHODS

A one-page questionnaire was sent to 1600 oral healthcare practitioners registered under the Indian Dental Association by using multistage sampling; 552 (34.5%) responded to the survey. The data were analysed using the χ(2) test and multiple logistic regression analysis.

RESULTS

Of 552 questionnaire respondents, 405 (73.4%) chose amoxicillin in non-allergic patients, alone [279 (50.5%)] or associated with clavulanic acid [126 (22.8%)]. The average duration of antibiotic therapy was 4.26 ± 1.26 days. The drug of first choice for patients with an allergy to penicillin was erythromycin [242 (43.8%) of respondents]. A majority prescribed antibiotics for irreversible pulpitis and acute apical periodontitis [395 (71.6%)] and necrotic pulp, acute apical periodontitis and no swelling [326 (59.1%)]. Five hundred and ten (92.4%) of the oral healthcare providers overprescribed antibiotics.

CONCLUSIONS

Oral healthcare providers in India are overprescribing, which could be a major contributor to the world problem of antimicrobial resistance. As there is overprescription of antibiotics by Indian oral healthcare providers, there is an urgent need to raise public and professional awareness regarding the risks of antibiotic use.

摘要

目的

医疗保健专业人员不恰当地开具抗生素是一个全球性的问题。本研究的目的是确定印度口腔保健提供者开具抗生素的模式。

方法

通过多阶段抽样向印度牙科协会注册的 1600 名口腔保健从业者发送了一份一页的问卷;有 552 人(34.5%)对调查做出了回应。使用 χ(2)检验和多因素逻辑回归分析对数据进行了分析。

结果

在 552 名问卷回答者中,405 名(73.4%)在非过敏患者中选择了阿莫西林,单独使用[279 名(50.5%)]或与克拉维酸联合使用[126 名(22.8%)]。抗生素治疗的平均持续时间为 4.26±1.26 天。对青霉素过敏患者的首选药物是红霉素[242 名(43.8%)的回答者]。大多数人对不可逆性牙髓炎和急性根尖周炎[395 名(71.6%)]和坏死牙髓、急性根尖周炎和无肿胀[326 名(59.1%)]开具了抗生素。510 名(92.4%)口腔保健提供者开具了过多的抗生素。

结论

印度的口腔保健提供者过度开具抗生素,这可能是导致全球抗生素耐药性问题的一个主要因素。由于印度口腔保健提供者过度开具抗生素,迫切需要提高公众和专业人员对抗生素使用风险的认识。

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