Oreja-Guevara Celia, Montalban Xavier, de Andrés Clara, Casanova-Estruch Bonaventura, Muñoz-García Delicias, García Inmaculada, Fernández Óscar
Hospital Clinico San Carlos, 28040 Madrid, Espana.
Rev Neurol. 2013 Oct 16;57(8):359-73.
Multiple sclerosis is a chronic neurological inflammatory demyelinating disease. Specialists involved in the symptomatic treatment of this disease tend to apply heterogeneous diagnostic and treatment criteria.
To establish homogeneous criteria for treating spasticity based on available scientific knowledge, facilitating decision-making in regular clinical practice.
A group of multiple sclerosis specialists from the Spanish Neurological Society demyelinating diseases working group met to review aspects related to spasticity in this disease and draw up the consensus. After an exhaustive bibliographic search and following a metaplan technique, a number of preliminary recommendations were established to incorporate into the document. Finally, each argument was classified depending on the degree of recommendation according to the SIGN (Scottish Intercollegiate Guidelines Network) system. The resulting text was submitted for review by the demyelinating disease group. An experts' consensus was reached regarding spasticity triggering factors, related symptoms, diagnostic criteria, assessment methods, quality of life and therapeutic management (drug and non-drug) criteria.
The recommendations included in this consensus can be a useful tool for improving the quality of life of multiple sclerosis patients, as they enable improved diagnosis and treatment of spasticity.
多发性硬化症是一种慢性神经炎性脱髓鞘疾病。参与该疾病对症治疗的专家倾向于采用不同的诊断和治疗标准。
基于现有科学知识制定统一的痉挛治疗标准,以促进常规临床实践中的决策制定。
来自西班牙神经学会脱髓鞘疾病工作组的一组多发性硬化症专家开会,回顾了该疾病中与痉挛相关的方面并达成共识。在进行详尽的文献检索并采用元计划技术后,制定了一些初步建议以纳入文件。最后,根据SIGN(苏格兰校际指南网络)系统,根据推荐程度对每个论点进行分类。生成的文本提交给脱髓鞘疾病组进行审查。就痉挛触发因素、相关症状、诊断标准、评估方法、生活质量和治疗管理(药物和非药物)标准达成了专家共识。
本共识中的建议可成为改善多发性硬化症患者生活质量的有用工具,因为它们有助于改善痉挛的诊断和治疗。