Doshi Bhavana, Mahajan Sunanda, Khopkar Uday S, Kharkar Vidya, Agarwal Prachi
Department of Dermatology, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, India.
Indian J Dermatol. 2013 Sep;58(5):396-9. doi: 10.4103/0019-5154.117323.
Melanoma is a rare form of cutaneous malignancy encountered in the dark skin population. Epidermotropic metastatic melanoma is a rare form of cutaneous metastatic melanoma which can mimic primary melanoma on histopathology. Hence its differentiation is of immense prognostic importance. The occurrence of rim of depigmentation around the primary cutaneous melanoma has previously been reported to portend a bad prognosis. The occurrence of vitiligo like lesions in patients with metastatic melanoma in comparison has a better prognosis. However the occurrence of depigmentation around the secondaries is rare and its importance is not well known. Hence we wish to report a case of epidermotropic metastatic melanoma with perilesional depigmentation in a 78 year old Indian male.
黑色素瘤是深色皮肤人群中罕见的一种皮肤恶性肿瘤。亲表皮转移性黑色素瘤是一种罕见的皮肤转移性黑色素瘤,在组织病理学上可类似于原发性黑色素瘤。因此,对其进行鉴别具有极其重要的预后意义。先前有报道称,原发性皮肤黑色素瘤周围出现色素脱失边缘预示预后不良。相比之下,转移性黑色素瘤患者出现白癜风样皮损预后较好。然而,继发性皮损周围出现色素脱失的情况罕见,其重要性也鲜为人知。因此,我们希望报告一例78岁印度男性亲表皮转移性黑色素瘤伴病灶周围色素脱失的病例。