Said Noor Hanif, Wong Siew Ngoh, Tan Wei Hsia
Department of Dermatology, National Skin Centre, Mandalay Road, Singapore.
Indian J Dermatol. 2013 Sep;58(5):405. doi: 10.4103/0019-5154.117316.
Adult onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology characterized by spiking fever, evanescent skin rash, arthralgia or arthritis, involvement of various organs, and predominantly neutrophilic leucocytosis. AOSD, although uncommon, has a characteristic constellation of clinical and laboratory features and should be considered in the differential diagnosis of pyrexia of unknown origin associated with a rash and arthralgia. The diagnosis is one of clinical suspicion and it is essential that infections, malignancy, and other rheumatic diseases are excluded. We report a case which illustrates the typical features of AOSD that were treated with steroids and azathioprine.
成人斯蒂尔病（AOSD）是一种病因不明的全身性炎症性疾病，其特征为高热、一过性皮疹、关节痛或关节炎、多器官受累以及以中性粒细胞增多为主。AOSD虽不常见，但具有一系列特征性的临床和实验室表现，在鉴别诊断不明原因发热伴皮疹和关节痛时应予以考虑。诊断主要基于临床怀疑，必须排除感染、恶性肿瘤和其他风湿性疾病。我们报告一例病例，该病例展现了用类固醇和硫唑嘌呤治疗的AOSD的典型特征。
