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吉兰-巴雷综合征作为成人斯蒂尔病的非典型早期表现：一例报告

Guillain-Barre Syndrome as an Atypical Early Presentation of Adult-Onset Still's Disease: A Case Report.

作者信息

Al Kaakour Jamila, El-Kojok Chirine, El Mustapha Sara, Kheirallah Jean Claude

机构信息

Internal Medicine, Lebanese University Faculty of Medicine, Beirut, LBN.

Infectious Diseases, Lebanese University Faculty of Medicine, Beirut, LBN.

出版信息

Cureus. 2024 Jun 11;16(6):e62162. doi: 10.7759/cureus.62162. eCollection 2024 Jun.

DOI:10.7759/cureus.62162
PMID:38993449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11238750/
Abstract

Adult-onset Still's disease (AOSD) is a rare auto-inflammatory disorder with unknown pathophysiology. Although having a heterogeneous clinical spectrum, the major features of AOSD include fever, rash, and arthritis or arthralgia. Neurological involvement is rare in AOSD with aseptic meningitis being the most common presentation. Guillain-Barre syndrome (GBS) has never been reported as an early presentation of AOSD. Herein, we describe the case of a patient presenting with GBS and fever of unknown origin who was soon diagnosed with AOSD and improved with corticosteroid therapy.

摘要

成人斯蒂尔病（AOSD）是一种罕见的自身炎症性疾病，其病理生理学尚不清楚。尽管AOSD具有异质性临床谱，但主要特征包括发热、皮疹和关节炎或关节痛。神经系统受累在AOSD中罕见，无菌性脑膜炎是最常见的表现。格林-巴利综合征（GBS）从未被报道为AOSD的早期表现。在此，我们描述了一例以GBS和不明原因发热为表现的患者，该患者很快被诊断为AOSD，并通过皮质类固醇治疗后病情好转。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8696/11238750/c5655a98d849/cureus-0016-00000062162-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8696/11238750/c5655a98d849/cureus-0016-00000062162-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8696/11238750/c5655a98d849/cureus-0016-00000062162-i01.jpg

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Adult-onset Still's disease with neurological involvement: a single-centre report.成人斯蒂尔病伴神经系统受累：单中心报告。
Rheumatology (Oxford). 2021 Sep 1;60(9):4152-4157. doi: 10.1093/rheumatology/keaa899.
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Aseptic meningitis and focal central nervous system involvement in a case of adult onset Still's disease.一例成人斯蒂尔病患者出现无菌性脑膜炎和局灶性中枢神经系统受累
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