Anderson P, Voss A, Hørder M
Odense Sygehus, klinisk kemisk afdeling.
Ugeskr Laeger. 1990 Feb 19;152(8):523-6.
By means of search in the literature and subsequent meta-analysis, the authors have described the serum total cholesterol values in three different risk groups for cardiovascular disease. High total serum cholesterol levels were associated with increased risk for cardiovascular disease. In addition, it was found that serum total cholesterol increases with age in all groups. A distinct sex difference was observed in the majority of investigations: in the age groups under 25 years and over 50 years, women have higher serum total cholesterol values than men while, in the age group 25-50 years, men have higher values than women. In addition, administration of hormones produces higher serum total cholesterol levels in young women but lower serum total levels among older women. In Danish investigations of serum total cholesterol, the level of serum total cholesterol corresponds to the serum total cholesterol levels in high and middle risk groups for cardiovascular disease.
通过文献检索及后续的荟萃分析，作者描述了心血管疾病三个不同风险组的血清总胆固醇值。血清总胆固醇水平升高与心血管疾病风险增加相关。此外，研究发现所有组的血清总胆固醇均随年龄增长而升高。在大多数调查中观察到明显的性别差异：在25岁以下和50岁以上年龄组，女性的血清总胆固醇值高于男性，而在25 - 50岁年龄组，男性的血清总胆固醇值高于女性。此外，激素给药使年轻女性的血清总胆固醇水平升高，但使老年女性的血清总胆固醇水平降低。在丹麦对血清总胆固醇的调查中，血清总胆固醇水平与心血管疾病高、中风险组的血清总胆固醇水平相当。
