Ashraf Mohamad Javad, Azarpira Negar, Khademi Bighan, Abedi Elham, Hakimzadeh Afsoon, Valibeigi Bita
Pathology Department, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Iran Red Crescent Med J. 2013 Apr;15(4):363-6. doi: 10.5812/ircmj.2209. Epub 2013 Apr 5.
Extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. Most lesions occur in the head and neck, primarily in the upper aerodigestive tract. The nasal cavity and nasal septum are the most common sites of occurrence. In this report, three patients admitted in our clinic with history of nasal obstruction and/or epistaxis. Patients were diagnosed with extramedullary plasmacytoma and mass were completely excised. This entity usually occurred in 5th-6th decade of life. One of our patients, a young man, was completely asymptomatic and following a paroxysm of coughing, a polypoid mass was expectorated. The clinical and histopathologic findings of plasmacytoma are discussed. In order to exclude systemic involvement, systematic approach using clinical, laboratory, and radiologic investigations was performed. Extramedullary plasmacytoma of the nasal cavity is rare and should be considered in the differential diagnosis of nasal cavity masses especially in young age group.
髓外浆细胞瘤是一种罕见的肿瘤，其特征为浆细胞的单克隆增殖。大多数病变发生在头颈部，主要在上呼吸道消化道。鼻腔和鼻中隔是最常见的发病部位。在本报告中，三名患者因鼻塞和/或鼻出血病史入住我院。患者被诊断为髓外浆细胞瘤，肿块被完全切除。该实体通常发生在50至60岁。我们的一名患者是一名年轻男性，完全无症状，在一阵咳嗽后咳出一个息肉样肿块。讨论了浆细胞瘤的临床和组织病理学发现。为了排除全身受累，采用临床、实验室和影像学检查的系统方法进行了检查。鼻腔髓外浆细胞瘤罕见，在鼻腔肿块的鉴别诊断中应予以考虑，尤其是在年轻年龄组。
