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一例XYY三体综合征流产胎儿的胎盘检查结果:病例报告

The placenta findings from an XYY abortus: a case report.

作者信息

Fan Rong

机构信息

Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Riley Hospital for Children at IU Health, 705 Riley Hospital Dr, Suite 2536, Indianapolis, IN 46202-5200, USA.

出版信息

J Med Case Rep. 2013 Oct 1;7:228. doi: 10.1186/1752-1947-7-228.

Abstract

INTRODUCTION

The placenta morphology from an XYY pregnancy abortus has not been reported in the medical literature. This case report consists of the first detailed documentation. The reported case is also highly unusual because the mother had two prior pregnancies with fetuses being confirmed to have Zellweger syndrome and one prior molar pregnancy.

CASE PRESENTATION

A 43-year-old Caucasian woman presented for induction of labor secondary to diagnosis of XYY chromosomes by chorionic villus sample.

CONCLUSIONS

This is the first detailed observation of placenta morphology in an XYY abortus. Although not highly specific, the observation is very unique and should prompt further investigation of karyotyping of the fetus or infant because an XYY individual may be viable and grow to adulthood. The association of an XYY abortus and prior pregnancies with Zellweger syndrome and one prior molar pregnancy is also highly notable.

摘要

引言

医学文献中尚未报道过XYY妊娠流产胎儿的胎盘形态。本病例报告首次进行了详细记录。所报告的病例也非常罕见,因为母亲之前有两次怀孕,胎儿均被确诊患有泽尔韦格综合征,还有一次葡萄胎妊娠。

病例介绍

一名43岁的白人女性因绒毛取样诊断为XYY染色体而前来引产。

结论

这是首次对XYY流产胎儿的胎盘形态进行详细观察。尽管观察结果并非高度特异,但非常独特,应促使对胎儿或婴儿进行进一步的核型分析,因为XYY个体可能存活至成年。XYY流产胎儿与之前的泽尔韦格综合征妊娠及一次葡萄胎妊娠之间的关联也非常值得注意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ac/4015697/6e4a4c4bc859/1752-1947-7-228-1.jpg

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