海洋来源真菌中的新型强效抗肿瘤天然产物：涵盖 2003 年至 2012 年期间的研究。
New and highly potent antitumor natural products from marine-derived fungi: covering the period from 2003 to 2012.
机构信息
University of Belgrade, Institute of Multidisciplinary Research - IMSI, Kneza Viseslava 1, 11030 Belgrade, Serbia.
出版信息
Curr Top Med Chem. 2013;13(21):2745-66. doi: 10.2174/15680266113136660197.
PMID:24083789
Abstract
This review covers the 2003-2012 literature data published for antitumor natural products from marine-derived fungi. The focus is on new and highly potent cytotoxic compounds, together with details related to the relevant fungal species. It describes 22 promising bioactives, originating mainly from symbiotic fungi. The chemical structures of all highlighted organic molecules are briefly discussed.
摘要
这篇综述涵盖了 2003 年至 2012 年期间发表的海洋来源真菌抗肿瘤天然产物的文献数据。重点介绍了新型、高效的细胞毒性化合物，以及与相关真菌物种相关的详细信息。它描述了 22 种有前途的生物活性物质，主要来源于共生真菌。所有突出显示的有机分子的化学结构都进行了简要讨论。
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