Kimura Y, Tadano T, Urano S, Yonezawa A, Watanabe H, Kisara K
Andrologia. 1985 Mar-Apr;17(2):166-71. doi: 10.1111/j.1439-0272.1985.tb00979.x.
Alpha-methyldopa causes inhibition of ejaculation by suppressing the dopaminergic system in the brain. The spinal mechanism which works together with this brain inhibitory mechanism was persued by determining the changes of spinal monoamines in dogs. As a result, it was found that suppression of the dopaminergic system by alpha-methyldopa is caused also in the spinal cord just as in the brain and that this suppression can be a direct origin of the inhibition of ejaculation.
α-甲基多巴通过抑制大脑中的多巴胺能系统来抑制射精。通过测定狗脊髓单胺类物质的变化,探究了与这种大脑抑制机制协同作用的脊髓机制。结果发现,α-甲基多巴对多巴胺能系统的抑制在脊髓中也如同在大脑中一样发生,并且这种抑制可能是射精抑制的直接根源。