关于α-甲基多巴对射精的抑制作用。
On suppression of ejaculation by Alpha-methyldopa.
作者信息
Kimura Y, Tadano T, Urano S, Yonezawa A, Watanabe H, Kisara K
出版信息
Andrologia. 1984 Mar-Apr;16(2):118-23. doi: 10.1111/j.1439-0272.1984.tb00247.x.
Abstract
Alpha-methyldopa caused inhibition of ejaculation. The cerebral mechanism which induced the inhibition was pursued by determining changes of brain monoamines in dogs. As a result, suppression of the dopaminergic system in the brain by alpha-methyldopa is found to be the origin of the inhibition of ejaculation. This inhibition was recovered by L-dopa with pretreatment with a peripheral decarboxylase inhibitor.
摘要
α-甲基多巴可导致射精抑制。通过测定犬脑单胺类物质的变化来探究引起这种抑制的脑机制。结果发现，α-甲基多巴对脑内多巴胺能系统的抑制是射精抑制的根源。用外周脱羧酶抑制剂预处理后，左旋多巴可恢复这种抑制作用。
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