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老年乳腺癌的管理。

Breast cancer management in the elderly.

机构信息

Medical Oncology Department, Hospital Universitario Central de Asturias, C/Julian Clavería s/n, 33006, Oviedo, Spain,

出版信息

Clin Transl Oncol. 2014 Apr;16(4):351-61. doi: 10.1007/s12094-013-1113-2. Epub 2013 Oct 2.

DOI:10.1007/s12094-013-1113-2
PMID:24085574
Abstract

The increase in life expectancy in the western world means that we are faced with patients diagnosed with breast cancer in old age with increasing frequency. The management of these cases is a challenge for the oncologist, who must take into account the conditions associated with advanced age and the lack of trials in this population. In this review, we addressed the incorporation of geriatric assessment methods that may be useful in making decisions, the particular biological characteristics of breast cancer in elderly patients and their treatment in both localized and advanced disease. Finally, we collected recommendations based on scientific evidence regarding the monitoring and life-style after finishing treatment.

摘要

在西方世界,预期寿命的增加意味着我们越来越频繁地面对老年乳腺癌患者。这些病例的管理对肿瘤学家来说是一个挑战,他必须考虑到与高龄相关的条件和该人群中缺乏试验。在这篇综述中,我们探讨了纳入老年评估方法的可能性,这些方法可能有助于做出决策,以及老年乳腺癌患者的特殊生物学特征及其在局限性和晚期疾病中的治疗方法。最后,我们根据关于治疗结束后监测和生活方式的科学证据收集了建议。

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1
Breast cancer management in the elderly.老年乳腺癌的管理。
Clin Transl Oncol. 2014 Apr;16(4):351-61. doi: 10.1007/s12094-013-1113-2. Epub 2013 Oct 2.
2
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Approach and Management of Breast Cancer in the Elderly.老年乳腺癌的治疗方法与管理
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Int J Radiat Oncol Biol Phys. 2017 Jul 15;98(4):884-890. doi: 10.1016/j.ijrobp.2017.01.210. Epub 2017 Jan 29.
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Comprehensive geriatric assessment in elderly breast cancer patients.老年乳腺癌患者的全面老年评估。
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本文引用的文献

1
Treatment algorithms for hormone receptor-positive advanced breast cancer: applying the results from recent clinical trials into daily practice—insights, limitations, and moving forward.激素受体阳性晚期乳腺癌的治疗算法:将近期临床试验结果应用于日常实践——见解、局限性及未来展望
Am Soc Clin Oncol Educ Book. 2013. doi: 10.1200/EdBook_AM.2013.33.e20.
2
Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343.早期乳腺癌且年龄 70 岁及以上的女性行保乳手术加他莫昔芬与或不加放疗:CALGB 9343 的长期随访结果
J Clin Oncol. 2013 Jul 1;31(19):2382-7. doi: 10.1200/JCO.2012.45.2615. Epub 2013 May 20.
3
优化治疗腔面型转移性乳腺癌老年患者的专家共识。
Clin Transl Oncol. 2022 Jun;24(6):1033-1046. doi: 10.1007/s12094-021-02766-8. Epub 2022 Feb 1.
4
Evaluating anthracycline + taxane versus taxane-based chemotherapy in older women with node-negative triple-negative breast cancer: a SEER-Medicare study.评估蒽环类药物+紫杉烷与紫杉烷类化疗在淋巴结阴性三阴性乳腺癌老年女性中的疗效:一项 SEER-医疗保险研究。
Breast Cancer Res Treat. 2022 Jan;191(2):389-399. doi: 10.1007/s10549-021-06424-z. Epub 2021 Oct 27.
Combination anastrozole and fulvestrant in metastatic breast cancer.
阿那曲唑与氟维司群联合治疗转移性乳腺癌。
N Engl J Med. 2012 Aug 2;367(5):435-44. doi: 10.1056/NEJMoa1201622.
4
Chemotherapy (CT) and hormonotherapy (HT) as neoadjuvant treatment in luminal breast cancer patients: results from the GEICAM/2006-03, a multicenter, randomized, phase-II study.新辅助化疗和激素治疗在 luminal 型乳腺癌患者中的应用:来自 GEICAM/2006-03 的多中心、随机、Ⅱ期研究结果。
Ann Oncol. 2012 Dec;23(12):3069-3074. doi: 10.1093/annonc/mds132. Epub 2012 Jun 6.
5
Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials.不同化疗方案治疗早期乳腺癌的比较:123 项随机试验 10 万名女性长期结局的荟萃分析。
Lancet. 2012 Feb 4;379(9814):432-44. doi: 10.1016/S0140-6736(11)61625-5. Epub 2011 Dec 5.
6
Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score.预测老年患者化疗毒性的风险:高龄患者化疗风险评估量表 (CRASH) 评分。
Cancer. 2012 Jul 1;118(13):3377-86. doi: 10.1002/cncr.26646. Epub 2011 Nov 9.
7
Influence of comorbidities and age on risk of death without recurrence: a retrospective analysis of the Arimidex, Tamoxifen Alone or in Combination trial.合并症和年龄对无复发生存死亡风险的影响:阿那曲唑、他莫昔芬单药或联合治疗的回顾性分析。
J Clin Oncol. 2011 Nov 10;29(32):4266-72. doi: 10.1200/JCO.2011.35.5545. Epub 2011 Oct 11.
8
Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.原发性乳腺癌:ESMO诊断、治疗及随访临床实践指南
Ann Oncol. 2011 Sep;22 Suppl 6:vi12-24. doi: 10.1093/annonc/mdr371.
9
The decline in breast cancer mortality in Europe: an update (to 2009).欧洲乳腺癌死亡率的下降:最新情况(截至 2009 年)。
Breast. 2012 Feb;21(1):77-82. doi: 10.1016/j.breast.2011.08.001. Epub 2011 Sep 8.
10
Trastuzumab-related cardiotoxicity in the elderly: a role for cardiovascular risk factors.曲妥珠单抗相关的老年人心血管毒性:心血管危险因素的作用。
Ann Oncol. 2012 Apr;23(4):897-902. doi: 10.1093/annonc/mdr348. Epub 2011 Aug 9.