通过注射非胸腺依赖性半抗原-载体偶联物诱导7S类限制的半抗原特异性麻痹。
7S class-restricted hapten-specific paralysis by injection of thymus-independent hapten-carrier conjugate.
作者信息
Del Guercio P, Poirier M F, Thobie N
出版信息
J Immunol. 1975 Nov;115(5):1239-42.
PMID:240889
Abstract
The shift from IgM anti-hapten antibody production to IgG anti-hapten antibody production, subsequent to challenge with a T-dependent conjugate, is inhibited in mice by preimmunization with the T-independent DNP-LE conjugate. The results suggest that DNP on levan triggers off 19A T-independent anti-hapten precursors and paralyzes 7S T-dependent anti-hapten precursors.
摘要
在用T细胞依赖性结合物攻击后，从小鼠体内产生IgM抗半抗原抗体向产生IgG抗半抗原抗体的转变，会被用T细胞非依赖性DNP-LE结合物进行的预免疫所抑制。结果表明，果聚糖上的DNP触发了19A T细胞非依赖性抗半抗原前体，并使7S T细胞依赖性抗半抗原前体麻痹。
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7S class-restricted hapten-specific paralysis by injection of thymus-independent hapten-carrier conjugate.通过注射非胸腺依赖性半抗原-载体偶联物诱导7S类限制的半抗原特异性麻痹。
J Immunol. 1975 Nov;115(5):1239-42.
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引用本文的文献
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J Exp Med. 1976 Sep 1;144(3):654-61. doi: 10.1084/jem.144.3.654.
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