Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan.
Division of Urology, Fukushima Minami Junkankika Hospital, Fukushima, Japan.
Hypertens Res. 2014 Feb;37(2):139-44. doi: 10.1038/hr.2013.116. Epub 2013 Oct 3.
A major earthquake measuring 9.0 on the Richter scale struck northeastern Japan at 2:46 pm on 11 March 2011. Several reports have described transient increases in blood pressure after major earthquakes, but the impact of such increases on hemodialysis patients has not been reported. We retrospectively investigated changes in blood pressure and influencing factors in 205 patients (mean age 66.6±13.0 years; male 51.7%; median dialysis vintage 6.0 (2.0-11.0) years) on chronic dialysis at three dialysis centers in the affected area (Fukushima City) for 8 weeks after the earthquake. Pre-dialysis blood pressure was significantly elevated at 1 week after the earthquake compared with baseline (systolic vs. diastolic blood pressure: 153.1±20.2/80.1±13.5 vs. 148.6±20.0/77.5±12.8 mm Hg, P<0.001), similarly post-dialysis blood pressure was elevated for up to 8 weeks. Independent factors influencing changes in blood pressure after the earthquake comprised baseline blood pressure and α-blockers. The earthquake induced a significant elevation in blood pressure among patients on chronic dialysis, and activation of the sympathetic nervous system might at least in part be associated with the mechanism underlying this increase.
2011 年 3 月 11 日下午 2 点 46 分，日本东北部发生里氏 9.0 级大地震。有几项报告描述了大地震后血压的短暂升高，但这种升高对血液透析患者的影响尚未报道。我们回顾性调查了震后 8 周内，3 个透析中心（福岛市）205 名（平均年龄 66.6±13.0 岁；男性 51.7%；中位透析时间 6.0[2.0-11.0]年）慢性透析患者的血压变化及其影响因素。与基线相比，地震后 1 周时透析前血压显著升高（收缩压与舒张压：153.1±20.2/80.1±13.5 比 148.6±20.0/77.5±12.8 mmHg，P<0.001），同样，透析后血压升高可持续 8 周。影响地震后血压变化的独立因素包括基线血压和α受体阻滞剂。地震导致慢性透析患者的血压显著升高，交感神经系统的激活可能至少部分与这种升高的机制有关。
