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2009 年拉奎拉地震引起的长期血压变化:24 小时动态监测评估。

Long-term blood pressure changes induced by the 2009 L'Aquila earthquake: assessment by 24 h ambulatory monitoring.

机构信息

Department of Life, Health and Environmental Sciences, University of L'Aquila, San Salvatore Hospital, L'Aquila, Italy.

出版信息

Hypertens Res. 2013 Sep;36(9):795-8. doi: 10.1038/hr.2013.37. Epub 2013 Apr 18.

Abstract

An increased rate of cardiovascular and cerebrovascular events has been described during and immediately after earthquakes. In this regard, few data are available on long-term blood pressure control in hypertensive outpatients after an earthquake. We evaluated the long-term effects of the April 2009 L'Aquila earthquake on blood pressure levels, as detected by 24 h ambulatory blood pressure monitoring. Before/after (mean±s.d. 6.9±4.5/14.2±5.1 months, respectively) the earthquake, the available 24 h ambulatory blood pressure monitoring data for the same patients were extracted from our database. Quake-related daily life discomforts were evaluated through interviews. We enrolled 47 patients (25 female, age 52±14 years), divided into three groups according to antihypertensive therapy changes after versus before the earthquake: unchanged therapy (n=24), increased therapy (n=17) and reduced therapy (n=6). Compared with before the quake, in the unchanged therapy group marked increases in 24 h (P=0.004), daytime (P=0.01) and nighttime (P=0.02) systolic blood pressure were observed after the quake. Corresponding changes in 24 h (P=0.005), daytime (P=0.01) and nighttime (P=0.009) diastolic blood pressure were observed. Daily life discomforts were reported more frequently in the unchanged therapy and increased therapy groups than the reduced therapy group (P=0.025 and P=0.018, respectively). In conclusion, this study shows that patients with unchanged therapy display marked blood pressure increments up to more than 1 year after an earthquake, as well as long-term quake-related discomfort. Our data suggest that particular attention to blood pressure levels and adequate therapy modifications should be considered after an earthquake, not only early after the event but also months later.

摘要

地震期间和之后,心血管和脑血管事件的发生率有所增加。在这方面,关于地震后高血压门诊患者的长期血压控制,仅有少量数据。我们评估了 2009 年 4 月拉奎拉地震对 24 小时动态血压监测所检测到的高血压患者血压水平的长期影响。在地震之前/之后(分别为平均±标准差 6.9±4.5/14.2±5.1 个月),从我们的数据库中提取了同一患者的可用 24 小时动态血压监测数据。通过访谈评估了与地震相关的日常生活不适。我们招募了 47 名患者(25 名女性,年龄 52±14 岁),根据地震前后抗高血压治疗的变化分为三组:治疗不变(n=24)、治疗增加(n=17)和治疗减少(n=6)。与地震前相比,在治疗不变组中,地震后 24 小时(P=0.004)、白天(P=0.01)和夜间(P=0.02)收缩压明显升高。相应的 24 小时(P=0.005)、白天(P=0.01)和夜间(P=0.009)舒张压也发生了变化。与治疗减少组相比,治疗不变组和治疗增加组报告的日常生活不适更频繁(P=0.025 和 P=0.018)。总之,本研究表明,治疗不变的患者在地震后 1 年以上仍显示出明显的血压升高,以及长期与地震相关的不适。我们的数据表明,不仅在事件发生后早期,而且在几个月后,都应特别注意血压水平和适当的治疗调整。

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