Samarut J, Nigon V
J Embryol Exp Morphol. 1975 Apr;33(2):259-78.
Irradiated chicken are injected with haemopoietic tissues from adult or 11-day-old embryos. Development of stem cells gives rise to well-defined erythrocytic colonies on the surface of the tibial marrow. Erythropoietic production appears to be similar from adult marrow and embryonic blood stem cells; production from injected vitelline stem cells seems to be between 3 and 4 times higher than that of adult marrow stem cells. Results are discussed on the basis of two hypotheses: -existence of an extramedullary erythropoietic site in the host after vitelline cells grafting; -development of vitelline stem cells in the host marrow with kinetic patterns different from those of grafted adult marrow or embryonic blood stem cells. Anyway, the 11-day-old embryo appears to contain at least two types of blood stem cells with distinctive properties. Developmental origin, relationship and future of these different stem cells remain to be analysed.
将辐照过的鸡注射成年或11日龄胚胎的造血组织。干细胞的发育会在胫骨骨髓表面产生界限分明的红细胞集落。成年骨髓和胚胎血干细胞的红细胞生成似乎相似；注射的卵黄干细胞的生成量似乎比成年骨髓干细胞高3至4倍。基于两种假设对结果进行了讨论：卵黄细胞移植后宿主存在髓外造血部位；宿主骨髓中卵黄干细胞的发育具有与移植的成年骨髓或胚胎血干细胞不同的动力学模式。无论如何，11日龄胚胎似乎至少含有两种具有独特特性的血干细胞。这些不同干细胞的发育起源、关系和未来仍有待分析。
