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先天性结核病:一种常见疾病的罕见表现。

Congenital tuberculosis: a rare manifestation of a common disease.

作者信息

Dewan Pooja, Gomber Sunil, Das Saurabhi

出版信息

Paediatr Int Child Health. 2014 Feb;34(1):60-2. doi: 10.1179/2046905513Y.0000000051. Epub 2013 Dec 6.

DOI:10.1179/2046905513Y.0000000051
PMID:24090923
Abstract

Congenital tuberculosis is difficult to diagnose unless there is a high index of suspicion. A 2-month-old infant boy presented with a history of fever since birth and failure to thrive. Chest radiograph demonstrated right upper lobe collapse/consolidation and an ultrasonogram of the abdomen showed multiple hypo-echoic hepatic and splenic lesions, and multiple retroperitoneal nodes. Fine needle aspiration of a cervical lymph node detected acid-fast bacilli (AFB). The mother's chest radiograph demonstrated features of pulmonary tuberculosis. Placental histology detected AFB. The combined clinical and laboratory features in both mother and infant supports the diagnosis of congenital tuberculosis.

摘要

先天性结核病很难诊断,除非高度怀疑。一名2个月大男婴自出生以来有发热病史且发育不良。胸部X光片显示右上叶肺不张/实变,腹部超声检查显示肝脏和脾脏有多个低回声病变以及多个腹膜后淋巴结。颈部淋巴结细针穿刺检测到抗酸杆菌(AFB)。母亲的胸部X光片显示有肺结核特征。胎盘组织学检查检测到抗酸杆菌。母亲和婴儿的临床及实验室综合特征支持先天性结核病的诊断。

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Indian Pediatr. 2021 Oct 15;58(10):991-992. doi: 10.1007/s13312-021-2337-9.
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Congenital Tuberculosis in a Neonate: A Case Report and Literature Review.新生儿先天性结核病:一例报告及文献综述
Front Pediatr. 2019 Jun 21;7:255. doi: 10.3389/fped.2019.00255. eCollection 2019.
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Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases.
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Orphanet J Rare Dis. 2019 Jun 10;14(1):131. doi: 10.1186/s13023-019-1101-x.
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A Perspective of the Diagnosis and Management of Congenital Tuberculosis.先天性结核病的诊断与管理视角
J Pathog. 2016;2016:8623825. doi: 10.1155/2016/8623825. Epub 2016 Nov 24.