From the Departments of Mental Health (LYC, RMC, and RM) and Epidemiology (RMC), Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; and Department of Psychiatry and Behavioral Sciences (ECS, RMC, and RM), Johns Hopkins University School of Medicine, Baltimore, MD.
J Addict Med. 2013 Sep-Oct;7(5):325-34. doi: 10.1097/ADM.0b013e31829b7afe.
To compare substance use disorders (SUD) treatment patterns and barriers to such treatment among men and women with SUD with and without comorbid major depressive episodes (MDE) in a community sample.
Using data from adult participants in the National Survey on Drug Use and Health 2005-2010, we investigated differences by sex in the association of MDE comorbidity with SUD on patterns of, perceived unmet need for, and the perceived barriers to SUD treatments.
Compared with participants with SUD without MDE, both men and women with comorbid SUD and MDE were more likely to use SUD services or to report an unmet need for such treatment. Sex modified the association of comorbidity and treatment patterns: males with MDE comorbidity had a greater likelihood of emergency room visits and use of inpatient services than females. Barriers to substance treatment were remarkably similar for males and females in both the SUD without MDE group and with MDE group, with attitudinal factors being the most common barriers.
Comorbidity with MDE seems to be an important predictor of service utilization and perceived need for SUD treatment in both men and women. The association of comorbidity with the use of some types of services, however, seems to vary according to sex. The findings have implications for the design of sex-specific SUD treatment programs.
在社区样本中,比较患有物质使用障碍(SUD)且伴或不伴共病重性抑郁发作(MDE)的男性和女性患者的 SUD 治疗模式和治疗障碍。
利用 2005-2010 年全国药物使用与健康调查的成年参与者数据,我们调查了 MDE 共病与 SUD 之间的关联在 SUD 治疗模式、感知未满足的需求和感知治疗障碍方面,是否存在性别差异。
与不伴 MDE 的 SUD 参与者相比,伴共病 MDE 的 SUD 男性和女性更有可能使用 SUD 服务或报告对这种治疗的未满足需求。性别改变了共病与治疗模式之间的关联:伴 MDE 共病的男性比女性更有可能到急诊室就诊和使用住院服务。在不伴 MDE 的 SUD 组和伴 MDE 组中,男性和女性对物质治疗的障碍非常相似,态度因素是最常见的障碍。
伴 MDE 的共病似乎是男性和女性患者获得 SUD 治疗服务和感知治疗需求的重要预测因素。然而,共病与某些类型服务的使用之间的关联似乎因性别而异。这些发现对设计特定于性别的 SUD 治疗方案具有重要意义。