Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Clin Infect Dis. 2014 Jan;58(2):e39-43. doi: 10.1093/cid/cit669. Epub 2013 Oct 2.
We describe the first report of temporally related cases of Bordetella holmesii bacteremia. Demographic and clinical data were collected through chart abstraction and case-patient interviews. Twenty-two cases were identified from 6 states. Symptom onset dates ranged from April 2010 to January 2011. Median age of patients was 17.1 years and 64% had functional or anatomic asplenia. Pulsed-field gel electrophoresis profiles of a sample of isolates were identical. These cases occurred during a peak in pertussis outbreaks with documented cases of B. holmesii/Bordetella pertussis respiratory coinfection; whether there is a link between B. holmesii respiratory and bloodstream infection is unknown.
我们描述了首例与时间相关的博德特氏菌属霍姆斯菌菌血症病例。通过图表提取和病例访谈收集人口统计学和临床数据。从 6 个州确定了 22 例病例。症状发作日期范围从 2010 年 4 月至 2011 年 1 月。患者的中位年龄为 17.1 岁，64%的患者有功能性或解剖性脾切除。分离株的脉冲场凝胶电泳图谱完全相同。这些病例发生在百日咳暴发高峰期，有记录的博德特氏菌属霍姆斯菌/百日咳博德特氏菌呼吸道合并感染病例；博德特氏菌属霍姆斯菌呼吸道感染与血流感染之间是否存在关联尚不清楚。
