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镰状细胞病患者内源性眼内炎的罕见病因

: An Unusual Cause of Endogenous Endophthalmitis in a Patient With Sickle Cell Disease.

作者信息

Pegany Roma B, George Roshan T, Zhang Alice Yang

机构信息

Department of Ophthalmology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.

出版信息

J Vitreoretin Dis. 2020 Sep 10;5(6):539-541. doi: 10.1177/2474126420946637. eCollection 2021 Nov-Dec.

DOI:10.1177/2474126420946637
PMID:37007180
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9976154/
Abstract

PURPOSE

This case report describes a rare organism causing endogenous endophthalmitis in a patient with sickle cell disease.

METHODS

A case report was conducted.

RESULTS

A 41-year-old man with sickle cell disease presented with acute onset of blurry vision of the right eye. His visual acuity was counting fingers in the right eye and 20/20 in the left eye. He had ophthalmic findings of hypopyon and vitritis in the right eye, consistent with endophthalmitis. He was treated with intravitreal and systemic antibiotics. Vitreous cultures grew . His visual acuity at follow-up visits improved to 20/40 in the setting of improved vitritis.

CONCLUSIONS

This is the first case describing , a rare causative organism of endogenous endophthalmitis, in a patient with sickle cell disease. More studies are needed to improve the early detection and treatment of this unusual organism.

摘要

目的

本病例报告描述了一种罕见的病原体,它在一名镰状细胞病患者中引发了内源性眼内炎。

方法

进行了一例病例报告。

结果

一名41岁的镰状细胞病男性患者出现右眼视力模糊的急性发作。他的右眼视力为眼前指数,左眼视力为20/20。他的右眼有前房积脓和玻璃体炎的眼科检查结果,与眼内炎相符。他接受了玻璃体内和全身抗生素治疗。玻璃体培养生长出……在玻璃体炎改善的情况下,他随访时的视力提高到了20/40。

结论

这是第一例描述……(一种内源性眼内炎的罕见病原体)在镰状细胞病患者中的病例。需要更多研究来改善对这种不寻常病原体的早期检测和治疗。

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本文引用的文献

1
Life-Threatening Infectious Complications in Sickle Cell Disease: A Concise Narrative Review.镰状细胞病的危及生命的感染性并发症:简明叙述性综述
Front Pediatr. 2020 Feb 20;8:38. doi: 10.3389/fped.2020.00038. eCollection 2020.
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Neuroimaging of ocular involvement in patients with sickle cell disease and review of the literature.镰状细胞病患者眼部受累的神经影像学及文献综述
Neuroradiol J. 2017 Feb;30(1):92-95. doi: 10.1177/1971400916678242. Epub 2017 Jan 3.
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Bordetella holmesii: Still Emerging and Elusive 20 Years On.支气管败血波氏杆菌:20 年后依然神秘且不断出现
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Endogenous endophthalmitis: diagnosis, management, and prognosis.内源性眼内炎:诊断、治疗与预后
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Bordetella holmesii: an under-recognised Bordetella species.支气管败血波氏杆菌:一种被低估的博德特氏菌。
Lancet Infect Dis. 2014 Jun;14(6):510-9. doi: 10.1016/S1473-3099(14)70021-0. Epub 2014 Apr 7.
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Bordetella holmesii bacteremia cases in the United States, April 2010-January 2011.美国 2010 年 4 月至 2011 年 1 月期间发生的博德特氏菌属霍姆斯菌菌血症病例。
Clin Infect Dis. 2014 Jan;58(2):e39-43. doi: 10.1093/cid/cit669. Epub 2013 Oct 2.
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Bordetella holmesii: a rare cause of bacterial endocarditis in a post-splenectomy patient.霍氏博德特菌:脾切除术后患者细菌性心内膜炎的罕见病因。
BMJ Case Rep. 2010 May 6;2010:bcr11.2009.2459. doi: 10.1136/bcr.11.2009.2459.
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Early intravitreal treatment of endogenous bacterial endophthalmitis.早期玻璃体内治疗内源性细菌性眼内炎。
Clin Exp Ophthalmol. 2011 Nov;39(8):771-8. doi: 10.1111/j.1442-9071.2011.02545.x. Epub 2011 Apr 21.
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Bordetella holmesii bacteremia in asplenic children: report of four cases initially misidentified as Acinetobacter lwoffii.脾切除术后儿童中霍氏博德特菌菌血症:4 例最初误诊为鲁氏不动杆菌的报告。
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Bordetella holmesii bacteremia in sickle cell disease.镰状细胞病中的霍氏博德特菌血症
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