Murao T, Misumi T, Yasuhara M
Gan No Rinsho. 1985 Apr;31(4):420-4.
A 70-year-old woman underwent modified radical mastectomy following excisional biopsy of a right breast mass. The excised tumor was 1.4 cm in diameter. The mastectomy specimen and lymph nodes were negative for malignancy. Histologically, the tumor cells were mainly oval and had formed solid nests in the thick fibrous stroma. The cytoplasm was fine granular and contained many argyrophilic granules. The argentaffin reaction was negative. Electron microscopy revealed oval-shaped light cells and stellate-shaped dark cells. Both types of tumor cells contained abundant filaments, well-developed rough surfaced endoplasmic reticulum and many neurosecretory-type granules measuring 190 approximately 360 nm in diameter. Intracytoplasmic lumina were not discerned. The relationship between carcinoid and conventional breast carcinoma was discussed.
一名70岁女性在对右侧乳腺肿块进行切除活检后接受了改良根治性乳房切除术。切除的肿瘤直径为1.4厘米。乳房切除标本和淋巴结均未发现恶性肿瘤。组织学上,肿瘤细胞主要为椭圆形,在厚纤维基质中形成实性巢状结构。细胞质呈细颗粒状,含有许多嗜银颗粒。嗜银反应为阴性。电子显微镜检查显示椭圆形亮细胞和星状暗细胞。两种类型的肿瘤细胞均含有丰富的细丝、发育良好的粗面内质网以及许多直径约为190至360纳米的神经分泌型颗粒。未发现胞质内管腔。讨论了类癌与传统乳腺癌之间的关系。