复发性头颈癌经口激光显微手术的治疗结果
Outcomes of transoral laser microsurgery for recurrent head and neck cancer.
作者信息
Reynolds L F, Rigby M H, Trites J, Hart R, Taylor S M
机构信息
Division of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
出版信息
J Laryngol Otol. 2013 Oct;127(10):982-6. doi: 10.1017/S0022215113001953. Epub 2013 Oct 7.
OBJECTIVE
To report our outcomes with salvage CO2 laser surgery following recurrence of laryngeal and oropharyngeal cancer after radiotherapy.
METHOD
This study entailed a prospective review of patients treated with transoral laser microsurgery for recurrent laryngeal and oropharyngeal cancer between 2002 and 2010 at the Queen Elizabeth II Health Science Centre in Canada.
RESULTS
Sixteen patients were identified, with a mean follow up of 30.6 months. Five patients died of recurrence. Complications were common in patients with oropharyngeal cancer. The overall survival and disease-free survival rates at an average of 29.8 months follow up were 50 per cent and 68.8 per cent respectively.
CONCLUSION
Salvage surgery using transoral laser microsurgery should be considered in the management of patients with recurrent laryngeal and oropharyngeal cancer. This technique offers acceptable salvage rates with less comorbidity than other treatments.
目的
报告我们在放射治疗后喉癌和口咽癌复发时采用挽救性二氧化碳激光手术的治疗结果。
方法
本研究对2002年至2010年期间在加拿大伊丽莎白女王二世健康科学中心接受经口激光显微手术治疗复发性喉癌和口咽癌的患者进行了前瞻性评估。
结果
共确定了16例患者，平均随访30.6个月。5例患者死于复发。口咽癌患者并发症常见。平均随访29.8个月时，总生存率和无病生存率分别为50%和68.8%。
结论
对于复发性喉癌和口咽癌患者的治疗，应考虑采用经口激光显微手术进行挽救性手术。该技术提供了可接受的挽救率，且与其他治疗方法相比合并症较少。
Zotero 插件