Fletcher Laboratory, Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Thorn 528, Boston, MA 02115, USA; Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
Hematol Oncol Clin North Am. 2013 Oct;27(5):957-74. doi: 10.1016/j.hoc.2013.07.002. Epub 2013 Aug 26.
This article presents an overview of the current literature about the biology, pathology, and the clinical management of leiomyosarcoma. In addition, the article emphasizes and discusses the current systemic treatment options available for patients with leiomyosarcoma, which range from cytotoxic chemotherapy to target therapies. Particular leiomyosarcoma subtypes, such as uterine leiomyosarcoma and inferior vena cava leiomyosarcoma, are discussed separately.
本文概述了目前关于平滑肌肉瘤的生物学、病理学和临床管理的文献。此外，本文还强调并讨论了目前可用于平滑肌肉瘤患者的系统治疗选择，包括细胞毒性化疗到靶向治疗。还分别讨论了特定的平滑肌肉瘤亚型，如子宫平滑肌肉瘤和下腔静脉平滑肌肉瘤。
