采用骨折风险评估工具评估巴勒斯坦特定人群的 10 年骨折概率。
Estimation of 10-year probability bone fracture in a selected sample of Palestinian people using fracture risk assessment tool.
机构信息
Division of Pharmacology/ Toxicology, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
出版信息
BMC Musculoskelet Disord. 2013 Oct 5;14:284. doi: 10.1186/1471-2474-14-284.
BACKGROUND
The Fracture Risk Assessment (FRAX) tool has been developed by the World Health Organization (WHO) to calculate 10-year probability hip fracture (HP) or major osteoporotic fracture (MOF). The objective of this study was to assess the 10-year probability of MOF and HF among a selected sample of Palestinian people.
METHODS
A sample of 100 subjects was studied. Dual energy X-ray absorpitometry was performed to measure bone mineral density (BMD) which was then inserted into FRAX Palestine online WHO tool to calculate the 10-year probability of MOF and HF.
RESULTS
The median age of participants was 61.5 years and the majority (79%) were females. The median (interquartile range) of femoral hip BMD was 0.82 (0.76-0.92) g/cm². The mean vertebral and hip T scores were -1.41 ± 0.13 SDs and -0.91 ± 0.10 SDs respectively. About one fifth of the sample (21%) had vertebral osteoporosis and 5% had hip osteoporosis. The median (interquartile range) 10-year probability of MOF and HF based on BMD were 3.7 (2.43-6.18)%, and 0.30 (0.10-0.68)% respectively.
CONCLUSION
Osteoporosis is common among Palestinian people above 50 years old. Bone fracture prevention strategies and research should be a priority in Palestine. Using FRAX might be a helpful screening tool in primary healthcare centres in Palestine.
背景
骨折风险评估（FRAX）工具由世界卫生组织（WHO）开发，用于计算 10 年髋部骨折（HP）或主要骨质疏松性骨折（MOF）的概率。本研究的目的是评估选定的巴勒斯坦人群中 MOF 和 HF 的 10 年概率。
方法
研究了 100 名受试者的样本。进行双能 X 射线吸收法（DXA）以测量骨矿物质密度（BMD），然后将其插入 FRAX 巴勒斯坦在线 WHO 工具中，以计算 MOF 和 HF 的 10 年概率。
结果
参与者的中位年龄为 61.5 岁，大多数（79%）为女性。股骨髋部 BMD 的中位数（四分位间距）为 0.82（0.76-0.92）g/cm²。平均椎体和髋部 T 评分分别为-1.41±0.13 SD 和-0.91±0.10 SD。约五分之一的样本（21%）有椎体骨质疏松症，5%有髋部骨质疏松症。基于 BMD 的 MOF 和 HF 的中位数（四分位间距）为 3.7（2.43-6.18）%和 0.30（0.10-0.68）%。
结论
骨质疏松症在 50 岁以上的巴勒斯坦人中很常见。骨折预防策略和研究应成为巴勒斯坦的优先事项。FRAX 可能是巴勒斯坦初级保健中心有用的筛选工具。
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