Department of Medicine, Université de Montréal, 5415 Boulevard De l'Assomption, Montréal, Québec H1T 2M4, Canada; Respiratory Critical Care Group, Respiratory Health Network of the FRQS, Montréal, Québec, Canada.
Crit Care Clin. 2013 Oct;29(4):853-64. doi: 10.1016/j.ccc.2013.06.007. Epub 2013 Aug 20.
The incidence of candidemia and invasive Candida infections has increased substantially over the last 2 decades. These infections are associated with risk factors that characterize intensive care unit patients. Candidemia and invasive Candida are highly morbid and associated with significantly increased mortality. Outcomes in the intensive care setting depend on physician awareness and rapid intervention. The epidemiology of the disease, its diagnostic challenges, and management strategies, including prophylactic, preemptive, and definitive therapeutic approaches, are presented herein.
在过去的 20 年中,念珠菌血症和侵袭性念珠菌感染的发病率显著增加。这些感染与 ICU 患者的特征性危险因素有关。念珠菌血症和侵袭性念珠菌病的发病率很高,死亡率显著增加。重症监护环境中的结果取决于医生的认识和快速干预。本文介绍了该疾病的流行病学、诊断挑战和管理策略,包括预防、先发制人和确定性治疗方法。