Ruiz-Tovar Jaime, Zubiaga Lorea, Llavero Carolina, Diez María, Arroyo Antonio, Calpena Rafael
Department of Surgery, Bariatric Surgery Unit, General University Hospital Elche, Av. Fotógrafo Francisco Cano, 113, Bw 41 03540, Alicante, Spain,
Obes Surg. 2014 Mar;24(3):385-9. doi: 10.1007/s11695-013-1082-0.
Laparoscopic sleeve gastrectomy (LSG) has shown to be effective in serum triglycerides reduction and HDL cholesterol increase, but with little effect on total cholesterol and LDL cholesterol. Physical activity is recognized as an effective non-pharmacological intervention to reduce body fat mass and hypercholesterolemia.
A prospective observational study of all the patients undergoing LSG as bariatric technique between 2007 and 2012 was performed. All patients completed the Spanish Version of the Modifiable Physical Activity Questionnaire at two time points: baseline (pre-intervention) and 1 year after surgery, both in face-to-face interviews. Lipid profiles were monitored at the same time points.
A total of 50 patients were included in the study, 44 females (88 %) and six males (12 %) with a mean age of 42.7 ± 10.3 years. Comorbidities included dyslipidemia in 50 % (40 % hypercholesterolemia and 10 % hypertriglyceridemia). Preoperatively, four patients (8 %) reported moderately active physical activity and one patient (2 %) active physical exercise. The rest of the patients were sedentary. One year after surgery, 30 patients (60 %) performed any kind of active physical activity, while the rest were sedentary. Lipid profile 12 months after surgery showed significantly lower total cholesterol levels in the active group (182.8 mg/dl vs 220 mg/dl in the sedentary group; p = 0.003). LDL cholesterol levels were also lower in the active group (103.2 vs 133 mg/dl in the sedentary group; p = 0.015).
The performance of routine moderate physical activity in addition to LSG achieves a significant improvement in all parameters of the lipid profile.
腹腔镜袖状胃切除术（LSG）已被证明在降低血清甘油三酯和升高高密度脂蛋白胆固醇方面有效，但对总胆固醇和低密度脂蛋白胆固醇影响较小。体育活动被认为是减少体脂量和高胆固醇血症的一种有效的非药物干预措施。
对2007年至2012年间接受LSG作为减肥技术的所有患者进行了一项前瞻性观察研究。所有患者在两个时间点完成了西班牙语版的可改变体育活动问卷：基线（干预前）和手术后1年，均通过面对面访谈完成。在相同时间点监测血脂情况。
本研究共纳入50例患者，44例女性（88%）和6例男性（12%），平均年龄42.7±10.3岁。合并症包括50%的血脂异常（40%高胆固醇血症和10%高甘油三酯血症）。术前，4例患者（8%）报告有中度体育活动，1例患者（2%）有积极体育锻炼。其余患者久坐不动。术后1年，30例患者（60%）进行了任何形式的积极体育活动，其余患者久坐不动。术后12个月时，活动组的总胆固醇水平显著降低（活动组为182.8mg/dl，久坐组为220mg/dl；p = 0.003）。活动组的低密度脂蛋白胆固醇水平也较低（活动组为103.2，久坐组为133mg/dl；p = 0.015）。
除LSG外，进行常规适度体育活动可使血脂谱的所有参数得到显著改善。
