García-Unciti M, Martinez J A, Izquierdo M, Gorostiaga E M, Grijalba A, Ibañez J
Department of Nutrition and Food Sciences, University of Navarra, Pamplona, Spain.
Nutr Hosp. 2012 Sep-Oct;27(5):1511-20. doi: 10.3305/nh.2012.27.5.5921.
Lifestyle changes such as following a hypocaloric diet and regular physical exercise are recognized as effective non-pharmacological interventions to reduce body fat mass and prevent cardiovascular disease risk factors.
To evaluate the interactions of a higher protein (HP) vs. a lower protein (LP) diet with or without a concomitant progressive resistance training program (RT) on body composition and lipoprotein profile in hypercholesterolemic obese women.
Retrospective study derived from a 16-week randomized controlled-intervention clinical trial. Twenty five sedentary, obese (BMI: 30-40 kg/m²) women, aged 40-60 with hypercholesterolemia were assigned to a 4-arm trial using a 2 x 2 factorial design (Diet x Exercise). Prescribed diets had the same calorie restriction (-500 kcal/day), and were categorized according to protein content as: lower protein (< 22% daily energy intake, LP) vs. higher protein (> 22% daily energy intake, HP). Exercise comparisons involved habitual activity (control) vs. a 16-week supervised whole-body resistance training program (RT), two sessions/wk.
A significant decrease in weight and waist circumference was observed in all groups. A significant decrease in LDL-C and Total-Cholesterol levels was observed only when a LP diet was combined with a RT program, the RT being the most determining factor. Interestingly, an interaction between diet and exercise was found concerning LDL-C values.
In this study, resistance training plays a key role in improving LDL-C and Total-Cholesterol; however, a lower protein intake (< 22% of daily energy intake as proteins) was found to achieve a significantly greater reduction in LDL-C.
诸如遵循低热量饮食和定期进行体育锻炼等生活方式的改变,被认为是减少体脂量和预防心血管疾病风险因素的有效非药物干预措施。
评估高蛋白(HP)与低蛋白(LP)饮食,在有或没有同时进行渐进性抗阻训练计划(RT)的情况下,对高胆固醇血症肥胖女性身体成分和脂蛋白谱的相互作用。
回顾性研究源自一项为期16周的随机对照干预临床试验。25名久坐不动、肥胖(BMI:30 - 40 kg/m²)、年龄在40 - 60岁且患有高胆固醇血症的女性,采用2×2析因设计(饮食×运动)被分配到一个四臂试验中。规定的饮食有相同的热量限制(-500千卡/天),并根据蛋白质含量分为:低蛋白(<每日能量摄入量的22%,LP)与高蛋白(>每日能量摄入量的22%,HP)。运动比较包括习惯性活动(对照组)与一项为期16周的有监督的全身抗阻训练计划(RT),每周两次。
所有组的体重和腰围均显著下降。仅当LP饮食与RT计划相结合时,观察到LDL-C和总胆固醇水平显著下降,RT是最主要的决定因素。有趣的是,在LDL-C值方面发现了饮食与运动之间的相互作用。
在本研究中,抗阻训练在改善LDL-C和总胆固醇方面起关键作用;然而,发现较低的蛋白质摄入量(<每日能量摄入量的22%作为蛋白质)能使LDL-C有显著更大程度的降低。