Ph. Bertin, Rheumatology Department, Centre Hospitalier Universitaire Dupuytren, 2 avenue M-L-King, 87042 LIMOGES Cédex France, Email:
J Nutr Health Aging. 2013;17(8):681-6. doi: 10.1007/s12603-013-0338-7.
The main objective of the S.AGES (Elderly Subjects) cohort study is to describe the current therapeutic strategy for chronic pain in non-institutionalised elderly patients in France.
In this prospective cohort study, non-institutionalised patients aged 65 years and over with chronic pain were recruited by general practitioners (GP) across France. All medicinal and non- medicinal prescriptions were recorded at inclusion and will be followed up over 3 years via an eCRF. Data recorded at baseline are presented in this paper.
Two hundred and sixty GPs enrolled 1379 evaluable patients between June 3rd, 2009 and June 3rd, 2011. Pain was mainly of a mechanical nature, due to osteoarthritis or common back pain. 80% of the patients had moderate or severe pain. More than a third of patients were treated with a step 1 analgesic (mainly paracetamol), and approximately 30% received a step 2 analgesic (23% dextropropoxyphene and 40.3% tramadol/paracetamol combination). Only 3% received step 3 analgesics; this rate remained low even in patients with severe pain. The proportion of patients treated with an antiepileptic was higher in case of neuropathic pain. More than 25% of patients did not receive any analgesic medication.
The baseline S.AGES study results exhibit a well-balanced therapeutic management of chronic pain by GPs for ambulatory elderly patients. Clinicaltrials.org NCT01065909.
S.AGES（老年人）队列研究的主要目的是描述法国非住院老年慢性疼痛患者的当前治疗策略。
在这项前瞻性队列研究中，通过法国各地的全科医生招募年龄在 65 岁及以上患有慢性疼痛的非住院患者。在纳入时记录所有药物和非药物处方，并通过电子 CRF 随访 3 年。本文介绍了基线时记录的数据。
260 名全科医生在 2009 年 6 月 3 日至 2011 年 6 月 3 日期间招募了 1379 名可评估患者。疼痛主要为机械性疼痛，由骨关节炎或常见背痛引起。80%的患者有中度或重度疼痛。超过三分之一的患者接受了第 1 步镇痛治疗（主要为对乙酰氨基酚），约 30%接受了第 2 步镇痛治疗（23%右旋丙氧芬和 40.3%曲马多/对乙酰氨基酚联合）。只有 3%接受了第 3 步镇痛治疗；即使在疼痛剧烈的患者中，这一比例仍然很低。在伴有神经病理性疼痛的患者中，使用抗癫痫药物的比例较高。超过 25%的患者未接受任何镇痛药物治疗。
S.AGES 研究的基线结果显示，全科医生对门诊老年患者的慢性疼痛进行了均衡的治疗管理。Clinicaltrials.org NCT01065909。
