对面部表情的神经反应支持杏仁核在处理威胁中的作用。
Neural responses to facial expressions support the role of the amygdala in processing threat.
作者信息
Mattavelli Giulia, Sormaz Mladen, Flack Tessa, Asghar Aziz U R, Fan Siyan, Frey Julia, Manssuer Luis, Usten Deniz, Young Andrew W, Andrews Timothy J
机构信息
Department of Psychology, University of Milano-Bicocca, 20126 Milano, Italy, York Neuroimaging Centre, University of York, York YO10 5NY, UK, Department of Psychology, University of York, York YO10 5DD, UK, and Hull York Medical School, University of Hull, HU6 7RX Hull, UK Department of Psychology, University of Milano-Bicocca, 20126 Milano, Italy, York Neuroimaging Centre, University of York, York YO10 5NY, UK, Department of Psychology, University of York, York YO10 5DD, UK, and Hull York Medical School, University of Hull, HU6 7RX Hull, UK
Department of Psychology, University of Milano-Bicocca, 20126 Milano, Italy, York Neuroimaging Centre, University of York, York YO10 5NY, UK, Department of Psychology, University of York, York YO10 5DD, UK, and Hull York Medical School, University of Hull, HU6 7RX Hull, UK.
出版信息
Soc Cogn Affect Neurosci. 2014 Nov;9(11):1684-9. doi: 10.1093/scan/nst162. Epub 2013 Oct 4.
The amygdala is known to play an important role in the response to facial expressions that convey fear. However, it remains unclear whether the amygdala's response to fear reflects its role in the interpretation of danger and threat, or whether it is to some extent activated by all facial expressions of emotion. Previous attempts to address this issue using neuroimaging have been confounded by differences in the use of control stimuli across studies. Here, we address this issue using a block design functional magnetic resonance imaging paradigm, in which we compared the response to face images posing expressions of fear, anger, happiness, disgust and sadness with a range of control conditions. The responses in the amygdala to different facial expressions were compared with the responses to a non-face condition (buildings), to mildly happy faces and to neutral faces. Results showed that only fear and anger elicited significantly greater responses compared with the control conditions involving faces. Overall, these findings are consistent with the role of the amygdala in processing threat, rather than in the processing of all facial expressions of emotion, and demonstrate the critical importance of the choice of comparison condition to the pattern of results.
已知杏仁核在对传达恐惧的面部表情的反应中发挥重要作用。然而，杏仁核对恐惧的反应是反映其在危险和威胁解读中的作用，还是在某种程度上由所有情绪面部表情激活，仍不清楚。以往使用神经成像解决这一问题的尝试因各研究中对照刺激使用的差异而受到干扰。在此，我们使用组块设计功能磁共振成像范式来解决这个问题，在该范式中，我们将对呈现恐惧、愤怒、快乐、厌恶和悲伤表情的面部图像的反应与一系列对照条件进行比较。将杏仁核对不同面部表情的反应与对非面部条件（建筑物）、轻度快乐面孔和中性面孔的反应进行比较。结果表明，与涉及面部的对照条件相比，只有恐惧和愤怒引发了明显更大的反应。总体而言，这些发现与杏仁核在处理威胁而非所有情绪面部表情处理中的作用一致，并证明了比较条件的选择对结果模式的至关重要性。
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